THURSDAY 27 MAY 2010

10.00 - 10.30 Registration

Session 1: 10.30 - 11.15
Chair: G. Cali
Plenary Lecture: M. A. De Matteis
The multiple functions of the Golgi complex: not only a central station for membrane trafficking

Session 2: 11:15-12.45 Function 1
Chairs: L. Laimins and A. Macdonald
Speakers:
R. Schlegel
Vesicle Fusion: a unifying hypothesis for the activity of HPV-16 E5 protein

E. Auvinen
HPV-16 E5 oncogene alters cellular microRNA expression in human epithelial cells

L. F. Wetherhill
Ubiquitin-Independent Proteasomal Degradation of High-Risk HPV-16 E5

L. Nasir
BPV-1 E5 upregulates Matrix Metalloproteinase I (MMP-1) expression and contributes to the invasive phenotype of equine sarcoid fibroblasts.

12.45 - 14.30 Light Lunch

Session 3: 14.30-15.15
Chair: M. S.Campo
Plenary Lecture: P. Lambert
E5 and its partners in crime; Short Mysteries on Cervical Cancer
Sponsored by Association for International Cancer Research

15.15 - 15.45 Coffee break

Session 4: 15.45-17.15 Transformation
Chairs: A. Venuti and E. Auvinen
Speakers:
L. Laimins
Bap31 and A4 are Novel Targets of the HPV E5 protein

V. Fontaine
Effects of HPV-16 and HPV-6 E5 on survival, adhesion and invasion in trophoblast and cervical cells

B. P. Ceresa
HPV-16 E5 Initiates Cell Transformation through Cell- Cell Fusion

F. Belleudi
HPV-16 E5 affects epithelial growth and differentiation inhibiting the FGFR2b endocytic degradation

17.15 - 19.00 Poster session

20.00 - 23.00 Gala Dinner

FRIDAY 28 MAY 2010

Session 5: 09.00-09.45
Chair: F. Roperto
Plenary Lecture: M. S. Campo
E5 proteins and MHC class I: the enemy within

Session 6: 09.45-10.45 Function 2
Chairs: G. Borzacchiello and L. Nasir
Speakers:
S. Brandt
BPV-1 infection in horses also involves the epidermis

A. Corteggio
Signal transduction pathways in BPV E5 positive naturally occurring tumours

F. Roperto
BPV-2 E5 in circulating blood cells of cattle with bladder tumour

M. C. Peleteiro
Immunohistochemical evaluation of urinary bladder epithelial tumours from cows with enzootic haematuria

10.45 - 11.00 Coffee break

Session 7: 11.00-11.45
Chair: R. Schlegel
Plenary Lecture: D. Di Maio
Decoding and Reprogramming the BPV-1 E5 mini-oncoprotein

Session 8: 11.45-12.45 From basic to clinical research
Chairs: L. Mariani and S. Brandt
Speakers:
A. Venuti
HPV-16 E5 oncogene alters the therapeutic response to taxanes

R. Franconi
E5 therapeutic vaccine against BPV-associated tumors and diseases

L. Bogaert
In vitro and in vivo immunogenicity of BPV-1 E5 in a mouse model of equine sarcoids

END OF WORKSHOP